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Table 1 Histopathological analysis of lesions from DMBA/TPA-treated wild type and Dll4+/− mice

From: Incomplete Dll4/Notch signaling inhibition promotes functional angiogenesis supporting the growth of skin papillomas

Diagnosis

Wild-type

Dll4+/−

Squamous papilloma

68

112

SCC grade I

1

1

Total

69

113

  1. Results shown are from 182 lesions from WT and Dll4+/− littermates (n = 12 for each group) treated with a single initiation dose of 25 μg DMBA followed by 4 μg TPA twice a week for 19 weeks. SSC squamous cell carcinoma