Fig. 5

Colocalization of CD163⁺ TAMS with STAT1 in oral leukoplakia. Double-labeled fluorescent immunostaining for CD163 (green) and STAT1 or pSTAT1 (red) in oral leukoplakia with moderate dysplasia. The cells double-stained for both the anti-CD163 and anti-STAT1 antibodies are shown (a, yellow). These cells colocalized to the subepithelial lesion (original magnification: ×200). Scale bar = 100 μm. b Correlation between infiltrated STAT1⁺ and CD163⁺ cells in oral leukoplakia. Statistically significant differences were determined using Spearman’s rank correlation coefficient analysis (p = 0.0034). c The cells double-stained for both the anti-CD163 and anti-pSTAT1 antibodies are shown (arrow heads)