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Table 1 Correlation between ADORA2B expression and clinical classification

From: Adenosine A2b receptor promotes progression of human oral cancer

Clinical classification Total Results of immunostaining p value
No. patients (%)
ADORA2B negative ADORA2B positive
Age at surgery (years)
 <60 27 7 (26) 20 (74) 0.95
60, <70 26 8 (31) 18 (69)
70 47 13 (28) 34 (72)
Gender
 Male 64 21 (33) 43 (67) 0.24
 Female 36 7 (19) 29 (81)
T-primary tumor
 T1 8 3 (38) 5 (62) 0.02*
 T2 60 22 (37) 38 (63)
 T3 15 2 (13) 13 (87)
 T4 17 1 (6) 16 (94)
 T1 + T2 58 25 (43) 33 (57) 0.01*
 T3 + T4 32 3 (10) 29 (90)
N-regional lymph node
 N (negative) 58 14 (24) 44 (76) 0.39
 N (positive) 42 14 (33) 28 (67)
Stage
 I 7 3 (43) 4 (57) 0.54
 II 38 11 (29) 27 (71)
 III 17 4 (24) 13 (76)
 IV 38 10 (26) 28 (74)
Histopathologic type
 Well 64 15 (23) 49 (77) 0.25
 Moderately 31 11 (35) 20 (65)
 Poorly 5 2 (40) 3 (60)
Tumor site
 Gingiva 35 11 (31) 24 (69) 0.84
 Tongue 50 12 (24) 38 (76)
 Buccal mucosa 9 2 (22) 7 (78)
 Oral floor 6 3 (50) 3 (50)
  1. p < 0.05
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