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Table 1 Characteristics of patients

From: Limited predictive value of achieving beneficial plasma (Z)-endoxifen threshold level by CYP2D6 genotyping in tamoxifen-treated Polish women with breast cancer

 

Total N = 279

Number of patients (%)

Age at diagnosis, median (range years)

55 (25 – 95)

Duration of tamoxifen treatment, median (range months)

21.5 (1 – 70)

Tamoxifen therapy

 

 neoadjuvant

7 (2.5)

 adjuvant

258 (92.5)

 metastasis

14 (5)

Breast cancer treatment

 

 surgery

276 (98.9)

 received radiation

148 (53)

 received chemotherapy

232 (83.2)

Hormonal status at diagnosis

 

 premenopausal

81 (29)

 postmenopausal

115 (41.2)

 unknown

83 (29.7)

Tumor size

 

 T1

105 (37.6)

 T2

142 (50.9)

 T3

20 (7.2)

 T4

10 (3.6)

 unknown

2 (0.7)

Node status

 

 N 0

132 (47.3)

 N 1

112 (40.3)

 N 2 - 3

30 (10.8)

 unknown

5 (1.8)

Differential grade

 

 G1

39 (14)

 G2

129 (46.2)

 G3

67 (24)

 unknown

44 (15.8)

Histology

 

 ductal

205 (73.5)

 lobular

30 (10.8)

 other

38 (13.6)

 unknown

6 (2.2)

Hormone receptor status

 

 Estrogen+

269 (96.4)

 Progesterone+

238 (85.3)

 Both

230 (82.4)

HER2 status

 

 positive

64 (22.9)

 negative

210 (75.3)

 unknown

5 (1.8)

  1. Tumor characteristics were at diagnosis. HER2: human epidermal growth factor receptor 2