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Table 7 Impact of C1orf63 expression on OS in different groups of breast cancer patients. 182 patients were divided according to either TNM stage or PR expression. There were 74 patients with TNM I ~ II stages, 107 patients with TNM III ~ IV stages, 74 patients with PR positive expression and 107 patients with PR negative expression. The differences of OS rates were tested using the Kaplan–Meier method with log rank test

From: Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study

Group

C1orf63 expression

Patients

Events

OS rate (%)b

P (log-rank)

3-year (95 % CI)c

5-year (95 % CI)c

TNM stages (I ~ II)

Negative

58

7

94.5 (88.4, 100.0)

83.4 (71.6, 95.2)

0.432

 

Positive

16

2

87.5 (71.2, 100.0)

87.5 (71.2, 100.0)

 

TNM stages (III ~ IV)

Negative

80

43

58.0 (46.8, 69.2)

46.2 (33.9, 58.5)

0.036

 

Positive

27

6

80.0 (64.3, 95.7)

72.7 (53.1, 92.3)

 

PR positive

Negative

50

16

87.2 (77.6, 96.8)

70.0 (55.5, 84.5)

0.106

 

Positive

22

1

100a

83.3 (53.5, 100.0)

 

PR negative

Negative

85

32

65.8 (55.4, 76.2)

62.1 (51.1, 73.1)

0.906

 

Positive

22

7

65.0 (44.0, 86.0)

65.0 (44.0, 86.0)

 
  1. a No patients died before the first three years, and the OS was 100 % while the 95 % CI were failed to calculate; bOS rate: Overall survival rate; c95 % CI: 95 % Confidence Interval