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Table 2 Astrocytoma survival association with kallikrein protein expression

From: Prognostic significance of multiple kallikreins in high-grade astrocytoma

  Univariable Adjusteda
  HR 95 % CI P HR 95 % CI P
KLK1       
Intensity 0.93 0.49–1.78 0.83 1.10 0.54–2.23 0.80
Percent 1.21 0.81–1.80 0.36 1.41 0.92–2.15 0.11
IR 1.08 0.96–1.21 0.21 1.13 0.99–1.29 0.06
KLK6       
Intensity 0.89 0.42–1.90 0.77 0.73 0.32–1.68 0.46
Percent 1.63 1.06–2.50 0.03* 1.35 0.87–2.10 0.18
IR 1.16 1.02–1.31 0.02* 1.10 0.96–1.25 0.17
KLK7       
Intensity 1.25 0.61–2.56 0.54 0.95 0.45–2.03 0.90
Percent 1.96 0.91–4.22 0.09 1.91 0.87–4.19 0.11
IR 1.17 1.02–1.34 0.03* 1.10 0.95–1.28 0.20
KLK8       
Intensity 0.87 0.46–1.66 0.68 0.84 0.40–1.78 0.65
Percent 0.91 0.66–1.25 0.54 0.96 0.68–1.36 0.81
IR 0.98 0.83–1.16 0.81 0.95 0.77–1.17 0.61
KLK9       
Intensity 0.65 0.38–1.13 0.13 0.64 0.36–1.14 0.13
Percent 2.25 1.21–4.22 0.01* 1.68 0.86–3.30 0.13
IR 1.05 0.90–1.22 0.52 0.99 0.85–1.16 0.90
KLK10      
Intensity 1.14 0.59–2.20 0.70 0.99 0.46–2.12 0.97
Percent 0.99 0.66–1.48 0.94 1.10 0.72–1.69 0.67
IR 1.12 0.92–1.37 0.27 1.03 0.82–1.28 0.80
  1. Cox proportional hazards regression analysis assessing the association of kallikrein protein expression in 60 grade IV astrocytoma specimens. *P ≤ 0.03, Cox proportional hazards regression analysis
  2. aAdjusted for age, gender and performance score