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Table 2 Astrocytoma survival association with kallikrein protein expression

From: Prognostic significance of multiple kallikreins in high-grade astrocytoma

 

Univariable

Adjusteda

 

HR

95 % CI

P

HR

95 % CI

P

KLK1

      

Intensity

0.93

0.49–1.78

0.83

1.10

0.54–2.23

0.80

Percent

1.21

0.81–1.80

0.36

1.41

0.92–2.15

0.11

IR

1.08

0.96–1.21

0.21

1.13

0.99–1.29

0.06

KLK6

      

Intensity

0.89

0.42–1.90

0.77

0.73

0.32–1.68

0.46

Percent

1.63

1.06–2.50

0.03*

1.35

0.87–2.10

0.18

IR

1.16

1.02–1.31

0.02*

1.10

0.96–1.25

0.17

KLK7

      

Intensity

1.25

0.61–2.56

0.54

0.95

0.45–2.03

0.90

Percent

1.96

0.91–4.22

0.09

1.91

0.87–4.19

0.11

IR

1.17

1.02–1.34

0.03*

1.10

0.95–1.28

0.20

KLK8

      

Intensity

0.87

0.46–1.66

0.68

0.84

0.40–1.78

0.65

Percent

0.91

0.66–1.25

0.54

0.96

0.68–1.36

0.81

IR

0.98

0.83–1.16

0.81

0.95

0.77–1.17

0.61

KLK9

      

Intensity

0.65

0.38–1.13

0.13

0.64

0.36–1.14

0.13

Percent

2.25

1.21–4.22

0.01*

1.68

0.86–3.30

0.13

IR

1.05

0.90–1.22

0.52

0.99

0.85–1.16

0.90

KLK10

     

Intensity

1.14

0.59–2.20

0.70

0.99

0.46–2.12

0.97

Percent

0.99

0.66–1.48

0.94

1.10

0.72–1.69

0.67

IR

1.12

0.92–1.37

0.27

1.03

0.82–1.28

0.80

  1. Cox proportional hazards regression analysis assessing the association of kallikrein protein expression in 60 grade IV astrocytoma specimens. *P ≤ 0.03, Cox proportional hazards regression analysis
  2. aAdjusted for age, gender and performance score