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Table 4 Median values (95 % CI) of the texture and kinetic parameters

From: Texture analysis on MR images helps predicting non-response to NAC in breast cancer

  Normal tissue CR + PR NR p-valuea
Energy 58 [44; 74] 36 [33; 41] 45 [42; 55] 7.9 10−5
Entropy 157 [141; 172] 187 [181; 193] 175 [165; 180] 6.4 10−5
Contrast 8 [6; 10] 14 [11; 16] 13 [10; 16] 8.6 10−5
Homogeneity 165 [150; 176] 140 [134; 146] 149 [144; 156] 5.1 10−5
Correlation 22 [18; 29] 47 [42; 52] 47 [44; 50] 1.8 10−14
Inv. Diff. Moment 174 [161; 185] 148 [141; 153] 158 [153; 165] 4.2 10−5
Sum average 69 [65; 76] 119 [114; 124] 120 [109; 127] 3.6 10−19
Sum variance 70 [60; 76] 92 [88; 99] 97 [86; 110] 2.2 10−15
Difference variance 74 [67; 81] 87 [82; 93] 80 [78; 83] 4.6 10−3
SRE 0.009 [0.008; 0.009] 0.004 [0.0039; 0.0044] 0.0038 [0.0035; 0.0047] 6.2 10−19
LRE 126 [114; 144] 266 [246; 279] 284 [229; 309] 7.6 10−20
GLN 158 [137; 229] 432 [338; 589] 416 [298; 817] 1.2 10−10
RLN 71 [58; 86] 111 [74; 120] 105 [89; 205] 6.2 10−4
RP 0.68 [0.62; 0.72] 0.72 [0.71; 0.75] 0.70 [0.66; 0.73] 9.3 10−4
LGRE 0.75 [0.71; 0.78] 0.79 [0.78; 0.81] 0.77 [0.74; 0.80] 9.8 10−4
HGRE 3.11 [2.54; 3.99] 2.55 [2.33; 2.76] 2.83 [2.49; 3.34] 8.8 10−3
SRLGE 0.0060 [0.0056; 0.0067] 0.0033 [0.0031; 0.0034] 0.0030 [0.0028; 0.0036] 2.6 10−17
SRHGE 0.028 [0.024; 0.034] 0.011 [0.010; 0.012] 0.011 [0.009; 0.014] 6.4 10−18
LRLGE 93 [84; 101] 204 [189; 215] 214 [177; 251] 6.0 10−20
LRHGE 412 [343; 509] 679 [615; 745] 799 [592; 925] 1.9 10−9
Amplitude _ 75 [70; 80] 68 [59; 79] _
Wash-out _ 0.04 [0.03; 0.06] 0.04 [0.008; 0.070] _
Wash-in _ 0.72 [0.64; 0.83] 0.63 [0.42; 0.70] _
  1. Amplitude is given in arbitrary unit (AU), wash-in and wash-out in AU.s−1
  2. NR Non response, CR Complete response, PR Partial response
  3. aStatistical difference (Wilcoxon) between normal tissues and tumoral lesion