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Table 4 Median values (95 % CI) of the texture and kinetic parameters

From: Texture analysis on MR images helps predicting non-response to NAC in breast cancer

 

Normal tissue

CR + PR

NR

p-valuea

Energy

58 [44; 74]

36 [33; 41]

45 [42; 55]

7.9 10−5

Entropy

157 [141; 172]

187 [181; 193]

175 [165; 180]

6.4 10−5

Contrast

8 [6; 10]

14 [11; 16]

13 [10; 16]

8.6 10−5

Homogeneity

165 [150; 176]

140 [134; 146]

149 [144; 156]

5.1 10−5

Correlation

22 [18; 29]

47 [42; 52]

47 [44; 50]

1.8 10−14

Inv. Diff. Moment

174 [161; 185]

148 [141; 153]

158 [153; 165]

4.2 10−5

Sum average

69 [65; 76]

119 [114; 124]

120 [109; 127]

3.6 10−19

Sum variance

70 [60; 76]

92 [88; 99]

97 [86; 110]

2.2 10−15

Difference variance

74 [67; 81]

87 [82; 93]

80 [78; 83]

4.6 10−3

SRE

0.009 [0.008; 0.009]

0.004 [0.0039; 0.0044]

0.0038 [0.0035; 0.0047]

6.2 10−19

LRE

126 [114; 144]

266 [246; 279]

284 [229; 309]

7.6 10−20

GLN

158 [137; 229]

432 [338; 589]

416 [298; 817]

1.2 10−10

RLN

71 [58; 86]

111 [74; 120]

105 [89; 205]

6.2 10−4

RP

0.68 [0.62; 0.72]

0.72 [0.71; 0.75]

0.70 [0.66; 0.73]

9.3 10−4

LGRE

0.75 [0.71; 0.78]

0.79 [0.78; 0.81]

0.77 [0.74; 0.80]

9.8 10−4

HGRE

3.11 [2.54; 3.99]

2.55 [2.33; 2.76]

2.83 [2.49; 3.34]

8.8 10−3

SRLGE

0.0060 [0.0056; 0.0067]

0.0033 [0.0031; 0.0034]

0.0030 [0.0028; 0.0036]

2.6 10−17

SRHGE

0.028 [0.024; 0.034]

0.011 [0.010; 0.012]

0.011 [0.009; 0.014]

6.4 10−18

LRLGE

93 [84; 101]

204 [189; 215]

214 [177; 251]

6.0 10−20

LRHGE

412 [343; 509]

679 [615; 745]

799 [592; 925]

1.9 10−9

Amplitude

_

75 [70; 80]

68 [59; 79]

_

Wash-out

_

0.04 [0.03; 0.06]

0.04 [0.008; 0.070]

_

Wash-in

_

0.72 [0.64; 0.83]

0.63 [0.42; 0.70]

_

  1. Amplitude is given in arbitrary unit (AU), wash-in and wash-out in AU.s−1
  2. NR Non response, CR Complete response, PR Partial response
  3. aStatistical difference (Wilcoxon) between normal tissues and tumoral lesion