Skip to main content
Fig. 5 | BMC Cancer

Fig. 5

From: Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway

Fig. 5

Effects of miR-9 inhibition on liver cancer cellular properties. a Soft-agar colony formation assay; (b) cellular invasion assay and (c) tumor sphere formation assay in SNU-449 cells transfected with an antisense microRNA negative control (anti-miR-C) or an antisense microRNA-9 (anti-miR-9). d Effects of PPARA inhibition by an siRNA (siPPARA) or an siRNA negative control (siCtrl) on the ability of SNU-449 cells to form colonies in soft-agar and (e) SNU-449 cell invasiveness. All data are represented as mean ± SE. ***P < 0.001, **P < 0.01

Back to article page