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Fig. 6 | BMC Cancer

Fig. 6

From: Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4

Fig. 6

miR-10b and its target HDAC4 influence tamoxifen-induced apoptosis and cell viability. Effect of ectopic expression of miR-10b and HDAC4 on (a) apoptosis-induction and (b) viability of MCF-7 cells, and the effect of silencing of miR-10b and HDAC4 on (c) apoptosis-induction and (d) viability of MCF7TR cells. Tamoxifen treatment was for 48 h. PM, pre-miR-10b; AM, anti-miR-10b; HDAC4, HDAC cDNA; siHDAC4, siRNA against HDAC4

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BMC Cancer

ISSN: 1471-2407

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