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Fig. 5 | BMC Cancer

Fig. 5

From: Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4

Fig. 5

Effect of HDAC4 levels on tamoxifen-sensitivity. a siRNA against HDAC4 reduced its expression in MCF-7 cells. Functional role of HDAC4 and miR-10b on tamoxifen sensitivity in b MCF-7 and c MCF7TR cells. β-actin protein was used as protein loading control for Western blots. Tamoxifen treatment was done for 48 h at indicated doses. PM, pre-miR-10b; AM, anti-miR-10b; HDAC4, HDAC cDNA; siHDAC4, siRNA against HDAC4

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BMC Cancer

ISSN: 1471-2407

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