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Table 1 Results representing the annexin assay after treatment of pancreatic cancer cells with MFX/CFX

From: Moxifloxacin and ciprofloxacin induces S-phase arrest and augments apoptotic effects of cisplatin in human pancreatic cancer cells via ERK activation

MIA Pa Ca-2

24 h

48 h

Panc-1

24 h

48 h

0 μg/ml

5 ± 2 %

1.6 ± 0.5 %

0 μg/ml

5.2 ± 0.58 %

4.2 ± 2.7 %

MFX 100 μg/ml

4.3 ± 0.64 %

4.4 ± 0.85 %

MFX 100 μg/ml

2.1 ± 2.7 %

4.6 ± 3.5 %

MFX 200 μg/ml

4.9 ± 0.6 %

5.9 ± 0.4 %

MFX 200 μg/ml

3.3 ± 1.59 %

7.9 ± 1.2 %

MFX 400 μg/ml

12.8 ± 1.2 %

23.4 ± 2 %

MFX 400 μg/ml

13 ± 1.15 %

16.9 ± 1.99 %

CFX 100 μg/ml

7.5 ± 0.3 %

7.9 ± 2.45 %

CFX 100 μg/ml

9.2 ± 1.8 %

9.8 ± 1.5 %

CFX 200 μg/ml

13.8 ± 0.6 %

22.5 ± 2 %

CFX 200 μg/ml

19 ± 3.4 %

14.6 ± 0.78 %

CFX 400 μg/ml

18.2 ± 0.2 %

40.6 ± 2.2 %

CFX 400 μg/ml

20.5 ± 1.8 %

21.6 ± 1.4 %

  1. Values represent the percentage of apoptosis