Hazard Ratio | 95 % CI for HR | p-value | |
---|---|---|---|
Age | 1.01 | 0.97–1.04 | 0.78 |
Gleason score | 0.005 | ||
≤6, 3 + 4 | ref | ||
4 + 3, ≥8 | 2.59 | 1.53–4.40 | |
Tumor volume | 0.02 | ||
<10 % | ref | ||
10–19 % | 1.49 | 0.57–3.90 | |
20–29 % | 1.42 | 0.50–4.03 | |
30–39 % | 2.88 | 1.18–7.05 | |
≥40 % | 3.30 | 1.39–7.84 | |
Pathologic stage | <0.0001 | ||
T2 | ref | ||
T3a | 3.61 | 1.85–7.05 | |
T3b | 6.73 | 3.68–12.29 | |
Positive lymph node(s) | 3.58 | 1.62–7.89 | 0.007 |
Initial PSA (per ng/ml) | 1.00 | 0.99–1.01 | 0.90 |
Positive surgical margins | 1.63 | 0.96–2.77 | 0.07 |
CD147 expression (per 0.01 OD) | 0.61 | 0.44–0.82 | 0.002 |
E-cadherin expression (per 0.1 OD) | 0.41 | 0.24–0.68 | 0.0007 |