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Fig. 4 | BMC Cancer

Fig. 4

From: SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction

Fig. 4

SDF-1alpha mediates Rho GTPase and integrin modulation. a Western blot analysis. MDA-MB-231 cells, serum-starved for 24 h, were treated with various concentration of SDF-1α (50, 100 and 200 ng/ml). Western blots against RhoA, Rock2, Rac1 and cdc42 were performed. The pixel density of each band has been divided by the corresponding actin band and by the control of the experiment. b Western blot analysis. MDA-MB-231 cells, serum-starved for 24 h, were treated with various concentration of SDF-1α (50, 100 and 200 ng/ml) for 4 h. Western blots against intergrin αV, β1 and β3 were performed. The pixel density of each band has been divided by the corresponding actin band and by the control of the experiment

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