BMC Cancer

Table 4 Associations between expression of Class III β-tubulin, Sox2, and Survivin and response to chemotherapy^a in 100 SOEC patients

From: Overexpression of Class III β-tubulin, Sox2, and nuclear Survivin is predictive of taxane resistance in patients with stage III ovarian epithelial cancer

	Taxane-based group				Non-taxane-based group
	Total no.	PR	PD	P ^b	Total no.	PR	PD	P ^b
Class III β-tubulin				0.006*				0.145
Total no.	57	34	23		43	33	10
Positive	34	15	19		24	16	8
Negative	23	19	4		19	17	2
Sox2				0.007*				0.480
Total no.	57	34	23		43	33	10
Positive	40	19	21		25	18	7
Negative	17	15	2		18	15	3
Only nuclear Survivin				0.009*				0.390
Total no.	41	24	17		37	30	7
Positive	19	7	12		14	10	4
Negative	22	17	5		23	20	3
Only cytoplasmic Survivin				0.580				0.495
Total no.	27	20	7		27	23	4
Positive	5	3	2		4	3	1
Negative	22	17	5		23	20	3

^aResponse to chemotherapy in 100 SOEC patients includes partial response (PR) and progression of disease (PD). There were no patients with complete response (CR) or stable disease (SD)
^bCalculated by χ² test
*P < 0.05

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ISSN: 1471-2407

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