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Table 1 Patient related characteristics

From: Variation in guideline adherence in non-Hodgkin’s lymphoma care: impact of patient and hospital characteristics

Characteristics

Patients

(N TOTAL  = 423)

Patient factors

N

%

Male sex

242

57

Mean age, years (range)

423

66 (22–94)

Co-morbidities (≥1)

256

61

Objections (patient preferences)A

25

6

Good performance statusB

67

94

Tumor related factors

Previous malignancies

71

17

Extranodal involvement

258

61

High LDH levelC

171

44

Aberrant Hb levelD

173

42

Ann Arbor stage III/IV

268

68

Aggressive tumor

254

60

DLBCL tumor typeE

194

46

IPI score (intermediate-) highB

49

38

Professional related factors

In-hospital referral

270

64

Multidisciplinary team consultation

172

41

Discussed in pathology panel

137

33

Therapy usedF

319

75

  1. Abbreviations: LDH lactate-dehydrogenase, Hb Hemoglobin, DLBCL diffuse large B-cell lymphoma, IPI International Prognostic Index
  2. AExcluded from further analyses due to <10 % variation
  3. BExcluded from further analyses due to >50 % missings, based on
  4. WHO and Karnofsky scores
  5. CHigh LDH level is defined as >250 U/l
  6. DAberrant Hb level is defined as <8.5 or >11 mmol/l for males and<7.5 or >10 mmol/l for females
  7. ENon-DLBCL tumor types include follicular lymphoma (18 %),
  8. marginal zone B-cell lymphoma (11 %), mantle-cell lymphoma (5 %),
  9. lympho(plasma)cytic lymphoma (10 %), and miscellaneous (9 %)
  10. FThe watch-and-wait management was coded as ‘no therapy used’