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Fig. 5 | BMC Cancer

Fig. 5

From: Nrf2 is a potential prognostic marker and promotes proliferation and invasion in human hepatocellular carcinoma

Fig. 5

Effect of Nrf2 on cell invasion in vitro. a Bel-7402 cells transfected with shRNA-Nrf2 (shRNA-1757 or shRNA-2019) or control shRNA (shNC) were subjected to transwell invasion assays; b The invasive cell numbers are the average count of five random microscopic fields detected using the transwell invasion assay; c HepG2 cells transfected with Nrf2 expression plasmid (pEFGP-Nrf2-1 or pEFGP-Nrf2-2) or mock pEGFP plasmid (pEGFP-NC) were subjected to transwell invasion assays; d The invasive cell numbers are the average count of five random microscopic fields detected using the transwell invasion assay. Each bar represents the mean ± SD of the counts. e After shRNA-Nrf2 (shRNA-1757 or shRNA-2019)) or control shRNA (shNC) transduction, expression of MMP-9 were detected by western blot in Bel-7402 cells; f After Nrf2 expression plasmid (pEFGP-Nrf2-1 or pEFGP-Nrf2-2) or mock pEGFP plasmid (pEGFP-NC) transduction, expression of MMP-9 were detected by western blot in HepG2 cells. *P < 0.05 compared with control (Bel-7402 cells or HepG2 cells respectively) or shNC and pEGFP-NC

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