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Table 6 Pathway analysis of genetic changes in the ‘hypoxic only’ response to cisplatin in A2780 and A2780cis

From: Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer

Cell Line Pathway P-value Change in Expression
A2780 Apoptosis 0.001 Up-regulated
ABC Transporters 0.002
Amyotrophic Lateral Sclerosis 0.005
Small Cell Lung Cancer 0.02
p53 signalling 0.02
Pancreatic Cancer 0.02
Chronic Myeloid Leukemia 0.03
A2780cis Focal Adhesion 0.04
A2780 Systemic Lupus Erythematosus 0.02 Down-regulated
MAPK signalling <0.001
Cell Cycle 0.002
Steroid Biosynthesis 0.005
ErbB Signalling 0.01
Nitrogen Metabolism 0.02
Axon Guidance 0.02
Colorectal Cancer 0.03
Gap Junction 0.04
A2780cis Systemic Lupus Erythematosus <0.001
Valine, Leucine and Isoleucine degradation 0.004
Homologous Recombination 0.03
Oocyte meiosis 0.05
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