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Fig. 4 | BMC Cancer

Fig. 4

From: Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer

Fig. 4

Expression of potential and known hypoxia biomarkers in ovarian cancer samples. The expression of ANGPTL4 (a), HER3 (b) and HIF1α (c) was examined in 35 serous ovarian adenocarcinoma samples. The samples were divided into responders (n = 16), partial responders (n = 11) and non-responders (n = 8). Expression of ANGPTL4 trended towards up-regulation in partial and down-regulation in non-responders compared to responders to chemotherapy. Expression of HER3 trended towards down-regulation in partial and non-responders to chemotherapy compared to responders. Expression of HIF-1α trended towards down-regulation in non-responders compared to responders to chemotherapy. There were missing data in one patient for HER3 expression and in three patients for ANGPTL4 expression in the responder group; and in one patient for ANGPTL4 expression in the non-responder group

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