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Table 3 The correlations between the overall survival and various clinicopathological factors in the exploratory study

From: The prognostic significance of the postoperative prognostic nutritional index in patients with colorectal cancer

 

Univariate analysis

Multivariate analysis

 

Hazard Ratio

95 % CI

p-value

Hazard Ratio

95 % CI

p-value

Age (>70 years)

4.143

0.832–20.641

0.083

0.616

0.054–6.992

0.696

Gender (Female)

0.998

0.238–4.178

0.998

   

Location of primary tumor (Rectum)

1.260

0.315–5.040

0.744

   

Tumor depth (T4)

1.044

0.261–4.177

0.951

0.098

0.004–2.233

0.145

Histological type (Poorly, Mucinous)

1.929

0.389–9.571

0.422

0.928

0.064–13.370

0.956

The number of lymph node metastases (≥4)

6.656

1.643–26.960

0.008

21.560

1.584–293.440

0.021

Preoperative CEA (>5 ng/ml)

3.218

0.648–15.975

0.153

13.475

0.281–645.979

0.188

Preoperative CA19-9 (>37 U/ml)

1.023

0.187–5.602

0.979

   

Adjuvant chemotherapy (None)

1.540

0.368–6.447

0.555

13.021

1.076–157.523

0.044

The amount of blood lost (>250 ml)

1.896

0.453–7.942

0.381

   

Combination of pre and postoperative PNI (<45)

3.770

1.316–10.801

0.013

6.728

1.200–37.716

0.030

  1. CI confidence interval, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19–9, PNI prognostic nutritional index