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Table 3 The correlations between the overall survival and various clinicopathological factors in the exploratory study

From: The prognostic significance of the postoperative prognostic nutritional index in patients with colorectal cancer

  Univariate analysis Multivariate analysis
  Hazard Ratio 95 % CI p-value Hazard Ratio 95 % CI p-value
Age (>70 years) 4.143 0.832–20.641 0.083 0.616 0.054–6.992 0.696
Gender (Female) 0.998 0.238–4.178 0.998    
Location of primary tumor (Rectum) 1.260 0.315–5.040 0.744    
Tumor depth (T4) 1.044 0.261–4.177 0.951 0.098 0.004–2.233 0.145
Histological type (Poorly, Mucinous) 1.929 0.389–9.571 0.422 0.928 0.064–13.370 0.956
The number of lymph node metastases (≥4) 6.656 1.643–26.960 0.008 21.560 1.584–293.440 0.021
Preoperative CEA (>5 ng/ml) 3.218 0.648–15.975 0.153 13.475 0.281–645.979 0.188
Preoperative CA19-9 (>37 U/ml) 1.023 0.187–5.602 0.979    
Adjuvant chemotherapy (None) 1.540 0.368–6.447 0.555 13.021 1.076–157.523 0.044
The amount of blood lost (>250 ml) 1.896 0.453–7.942 0.381    
Combination of pre and postoperative PNI (<45) 3.770 1.316–10.801 0.013 6.728 1.200–37.716 0.030
  1. CI confidence interval, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19–9, PNI prognostic nutritional index