Fig. 3
The combination of Rap with Dex arrests Raji cells in the G0/G1 phase of the cell cycle. a Raji cells were incubated for 48 h with Rap (10 nM) and/or Dex (1 μM), and the cell cycle progression was analyzed by PI staining. For all experiments, values are presented as the mean ± SD (n = 3) *: p < 0.01 versus the control group, Dex group, or Rap group. b After 48 h exposure to Rap and/or Dex, cells were lysed and extracts were analyzed by western blotting. β-Actin was used as an internal control. c Bar graphs show the normalized intensity of the different proteins. Values are the results of 3 determinations. R, Rap; D, Dex; RD, Rap + Dex, and C, control