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Table 5 Host and bacterium variables associated with gastric cancer (n = 232) in comparison with H. pylori-positive blood donors (n = 370)

From: STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

Covariate Univariate analysis Multivariate analysis
p OR 95 % CI p
Age < 0.001 1.20 1.16 - 1.23 < 0.001
Gender < 0.001 2.99 1.48 - 6 0.002
rs744166 0.002 1.76 1.14 - 2.70 0.01
CagA +ve < 0.001 12.80 5.48 - 29.86 < 0.001
  1. The Hosmer-Lemeshow test showed good fit (10 steps; 8 degrees of freedom; p = 0.20). rs744166 genotype was treated as categorical variables having 3 values with 0 meaning the AA genotype, 1 the carrier of one G allele and 2 the GG genotype, +ve, positive