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Table 5 Host and bacterium variables associated with gastric cancer (n = 232) in comparison with H. pylori-positive blood donors (n = 370)

From: STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

Covariate

Univariate analysis

Multivariate analysis

p

OR

95 % CI

p

Age

< 0.001

1.20

1.16 - 1.23

< 0.001

Gender

< 0.001

2.99

1.48 - 6

0.002

rs744166

0.002

1.76

1.14 - 2.70

0.01

CagA +ve

< 0.001

12.80

5.48 - 29.86

< 0.001

  1. The Hosmer-Lemeshow test showed good fit (10 steps; 8 degrees of freedom; p = 0.20). rs744166 genotype was treated as categorical variables having 3 values with 0 meaning the AA genotype, 1 the carrier of one G allele and 2 the GG genotype, +ve, positive
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BMC Cancer

ISSN: 1471-2407

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