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Table 2 Distribution of the STAT3 rs744166 genotypes according to the gender, mean age, H. pylori status and CagA status in blood donors (n = 541)

From: STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

  Gender STAT3 genotypes
  Female Male AA AG GG Total
n (%) n (%) n (%) n (%) n (%) n (%)
Female 132 (24.4) - 39 (29.5) 63 (47.8) 30 (22.7) 132 (100)
Male - 409 (75.6) 142 (34.7) 187 (45.7) 80 (19.6) 409 (100)
total - - 181 (33.5) 250 (46.2) 110 (20.3) 541 (100)
Mean age in yrs (SD) 33.6 (9.9) 33.8 (9.6) 34.6 (10.3) 33.6 (9.8) 32.9 (9.8) 33.8 (10.0)
Range yrs 18 - 59 18 - 65 18 - 65 18 - 64 19 - 59 18 - 65
Hp -ve 53 (40.2) 118 (28.9) 53 (29.3) 81 (47.4) 37 (21.6) 171 (31.6)
Hp +ve 79 (59.8) 291 (71.1) 128 (34.6) 169 (45.7) 73 (19.7) 370 (68.4)
CagA -ve 34 (43.0) 126 (43.3) 51 (31.9) 77 (48.1) 32 (20.0) 160 (43.3)
CagA +ve 45 (57.0) 165 (56.7) 73 (34.8) 95 (45.2) 42 (20.0) 210 (56.7)
  1. n, number; SD, standard deviation; yrs, years; Hp, Helicobacter pylori; -ve, negative; +ve, positive