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Table 5 Apoptosis evaluation on mice’ kidneys and liver

From: A novel cytosporone 3-Heptyl-4,6-dihydroxy-3H-isobenzofuran-1-one: synthesis; toxicological, apoptotic and immunomodulatory properties; and potentiation of mutagenic damage

Experimental groups

Liver

Kidneys

Number of apoptotic cells

Mean ± SE

Number of apoptotic cells

Mean ± SE

Group 1

64

12.80 ± 2.40a

69

13.80 ± 1.88ª

Group 2

1349

269.80 ± 22.63b

1045

209.00 ± 42.42b

Group 3

978

195.60 ± 4.69b

1049

209.80 ± 8.63b

Group 4

1160

232.00 ± 20.38b

1070

214.00 ± 36.08b

Group 5

2272

454.40 ± 24.35c

2243

448.60 ± 24.92c

Group 6

2345

469.00 ± 38.45c

2480

496.00 ± 24.03c

Group 7

NA

NA

NA

NA

  1. SE: Standard error
  2. NA: Not analyzed
  3. Different letters indicate statistically significant differences (p < 0.05; ANOVA/Tukey)