Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors

BMC Cancer

Table 3 Univariate and multivariate overall survival Cox regression model with clinical parameters and profiles of TMEM expression in tumors. Total cases = 66, censored cases = 59. Abbreviations: HR – hazard ratio. 95 % CI HR – 95 % confidence interval. AIC – Akaike Information Criterion. n – number of samples. n events – number of deaths (i.e., cases not censored). VIF – variance inflation factor

Overall survival	Univariate							Multivariate
	p-value	q-value	HR	95 % CI HR		AIC	n (n events)	p-value	q-value	HR	95 % CI OR		AIC	n (n events)	VIF
	p-value	q-value	HR	Lower	Upper	AIC	n (n events)	p-value	q-value	HR	Lower	Upper	AIC	n (n events)	VIF
TMEM116 expression	0.008	0.086	0.554	0.358	0.856	44.85	66 (7)	0.082	0.319	7.167	0.777	66.147	18.60	61 (4)	4.915
Average tumor size [mm]	0.009	0.089	1.044	1.011	1.077	44.41	66 (7)	0.022	0.153	1.133	1.018	1.260			2.788
VHL expression	0.028	0.180	0.504	0.273	0.931	47.03	66 (7)	0.223	0.549	0.379	0.079	1.807			2.430
TMEM72 expression	0.048	0.186	0.736	0.543	0.997	24.52	61 (4)	0.045	0.239	0.390	0.155	0.980			3.806
SLC35G2 expression	0.067	0.244	0.825	0.671	1.014	48.63	65 (7)	Variables not in the multivariate model
TMEM61 expression	0.073	0.285	0.733	0.522	1.029	32.23	59 (5)
Symptoms	0.084	0.303	3.789	0.834	17.211	48.52	66 (7)

ISSN: 1471-2407