Skip to main content

Table 3 Univariate and multivariate overall survival Cox regression model with clinical parameters and profiles of TMEM expression in tumors. Total cases = 66, censored cases = 59. Abbreviations: HR – hazard ratio. 95 % CI HR – 95 % confidence interval. AIC – Akaike Information Criterion. n – number of samples. n events – number of deaths (i.e., cases not censored). VIF – variance inflation factor

From: Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors

Overall survival Univariate Multivariate
p-value q-value HR 95 % CI HR AIC n (n events) p-value q-value HR 95 % CI OR AIC n (n events) VIF
Lower Upper Lower Upper
TMEM116 expression 0.008 0.086 0.554 0.358 0.856 44.85 66 (7) 0.082 0.319 7.167 0.777 66.147 18.60 61 (4) 4.915
Average tumor size [mm] 0.009 0.089 1.044 1.011 1.077 44.41 66 (7) 0.022 0.153 1.133 1.018 1.260 2.788
VHL expression 0.028 0.180 0.504 0.273 0.931 47.03 66 (7) 0.223 0.549 0.379 0.079 1.807 2.430
TMEM72 expression 0.048 0.186 0.736 0.543 0.997 24.52 61 (4) 0.045 0.239 0.390 0.155 0.980 3.806
SLC35G2 expression 0.067 0.244 0.825 0.671 1.014 48.63 65 (7) Variables not in the multivariate model
TMEM61 expression 0.073 0.285 0.733 0.522 1.029 32.23 59 (5)
Symptoms 0.084 0.303 3.789 0.834 17.211 48.52 66 (7)