Table 1 Characterization of ccRCC patient cohort. Median age of healthy donors which PBMCs were obtained from was 42.50 years old, 25 % Percentile = 35, 75 % Percentile = 46.75. Abbreviations: NM – not measured
Name of the characteristic | Amount | ||
|---|---|---|---|
Tumor tissue | PBMCs before nephrectomy | PBMCs 12Â months post-nephrectomy | |
Number of samples included in the study | |||
Patients | 76 | 66 | 27 |
Controls | 23 | 14 | 14 |
Gender | |||
Males (%) | 45 (59) | 45 (68) | 19 (70) |
Females (%) | 31 (41) | 21 (32) | 8 (30) |
Age (at a time of surgery) | |||
Median | 64 | 65 | 61 |
25Â % Percentile | 57 | 56 | 53 |
75Â % Percentile | 72 | 73 | 69 |
Tumor size [mm] | |||
Median | 43 | 43.50 | 44 |
25Â % Percentile | 33 | 31.88 | 28.50 |
75Â % Percentile | 65.38 | 65 | 59 |
TNM stage – pT | |||
pT1 (%) | 40 (52) | 34 (51) | 16 (59) |
pT2 (%) | 2 (3) | 3 (5) | 2 (8) |
pT3 (%) | 32 (42) | 28 (42) | 9 (33) |
pT4 (%) | 2 (3) | 1 (2) | 0 (0) |
TNM stage – pN | |||
pN0 (%) | 73 (96) | 63 (95) | 27 (100) |
pN1 (%) | 3 (4) | 3 (5) | 0 |
TNM stage – M | |||
M0 (%) | 62 (82) | 52 (79) | 25 (93) |
M1 (%) | 14 (18) | 14 (21) | 2 (7) |
Fuhrman grade | |||
G1 (%) | 4 (6) | 4 (6) | 0 (0) |
G2 (%) | 35 (46) | 32 (48) | 17 (63) |
G3 (%) | 26 (34) | 22 (33) | 9 (33) |
G4 (%) | 11 (14) | 8 (13) | 1 (4) |
VHL expression | |||
VHL+ | 33 | NM | NM |
VHL- | 43 | NM | NM |