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Table 1 Characterization of ccRCC patient cohort. Median age of healthy donors which PBMCs were obtained from was 42.50 years old, 25 % Percentile = 35, 75 % Percentile = 46.75. Abbreviations: NM – not measured

From: Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors

Name of the characteristic Amount
Tumor tissue PBMCs before nephrectomy PBMCs 12 months post-nephrectomy
Number of samples included in the study
Patients 76 66 27
Controls 23 14 14
Gender
Males (%) 45 (59) 45 (68) 19 (70)
Females (%) 31 (41) 21 (32) 8 (30)
Age (at a time of surgery)
Median 64 65 61
25 % Percentile 57 56 53
75 % Percentile 72 73 69
Tumor size [mm]
Median 43 43.50 44
25 % Percentile 33 31.88 28.50
75 % Percentile 65.38 65 59
TNM stage – pT
pT1 (%) 40 (52) 34 (51) 16 (59)
pT2 (%) 2 (3) 3 (5) 2 (8)
pT3 (%) 32 (42) 28 (42) 9 (33)
pT4 (%) 2 (3) 1 (2) 0 (0)
TNM stage – pN
pN0 (%) 73 (96) 63 (95) 27 (100)
pN1 (%) 3 (4) 3 (5) 0
TNM stage – M
M0 (%) 62 (82) 52 (79) 25 (93)
M1 (%) 14 (18) 14 (21) 2 (7)
Fuhrman grade
G1 (%) 4 (6) 4 (6) 0 (0)
G2 (%) 35 (46) 32 (48) 17 (63)
G3 (%) 26 (34) 22 (33) 9 (33)
G4 (%) 11 (14) 8 (13) 1 (4)
VHL expression
VHL+ 33 NM NM
VHL- 43 NM NM