Fig. 1
Differential expression of TMEMs in tumor tissue. (a) A comparison of TMEM expression between a tumor tissue and healthy kidney tissue. (b) TMEM expression in metastatic and non-metastatic tumors. (c) TMEM expression in organ-confined and advanced stage tumors (d) TMEM expression in low Fuhrman grade and high Fuhrman grade samples. Average log2 relative expression data in each sample group ± standard error of mean is shown in each chart. FC – fold-change. n – number of samples. T – tumor tissue samples. C – healthy tissue samples. M0 – non-metastatic ccRCC. M1 – metastatic ccRCC tissues. pT1/pT2 – organ-confined tumors, as assessed by TNM staging system. pT3/pT4 – advanced tumors, as assessed by TNM staging system. G1/G2 – low Fuhrman grade samples. G3/G4 – high Furhman grade samples. * - q < 0.05. ** - q < 0.01. *** - q < 0.001. **** - q < 0.0001