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Table 1 Baseline of patient characteristics

From: Radical surgery versus standard surgery for primary cytoreduction of bulky stage IIIC and IV ovarian cancer: an observational study

Characteristic Radical surgery group Standard surgery group P value*
Median age (range) 56 years (35–82) 56 years (26–79) 1.000
FIGO stage    0.045
 Stage IIIC 91(81.2 %) 215(89.2 %)  
 Stage IV 21(18.8 %)b 26(10.8 %)  
Primary tumor    0.535
 Epithelial ovarian cancer 111 (99.1 %) 240 (99.6 %)  
 Fallopian tube cancer 1 (0.9 %) 0 (0 %)  
 Primary peritoneal cancer 0 (0 %) 1 (0.4 %)  
Histology    0.084
 Serous 100(89.3 %) 202(83.8 %)  
 Mucinous 0(0 %) 2(0.8 %)  
 Endometrioid 2(1.8 %) 2(0.8 %)  
 Clear cell 2(1.8 %) 5(2.1 %)  
 Others 8(7.2 %) 30(12.4 %)  
Grade    0.787
 Grade1 0(0 %) 2(0.8 %)  
 Grade 2 9(8.0 %) 16(6.6 %)  
 Grade 3 102(91.1 %) 218(90.5 %)  
 NA 1(0.9 %) 5(2.1 %)  
ECOG performance status    0.116
 0 57(50.9 %) 95(39.4 %)  
 1 49(43.8 %) 126(52.3 %)  
 2 6(5.4 %) 20(8.3 %)  
ASA status    0.358
 1 59(52.7 %) 107(44.4 %)  
 2 51(45.5 %) 127(52.7 %)  
 3 2(1.8 %) 7(2.9 %)  
Preoperative serum CA125    0.245
 Median serum level (range) 1320 U/ml (67.2–77050) 1725 U/ml (32.1–39145)  
Neoadjuvant chemotherapy    0.421
 Yes 20 (17.9 %) 35 (14.5 %)  
 No 92 (82.1 %) 206 (85.5 %)  
Ascites    0.472
 Median volume (range) 1350 ml (0–7000) 1500 ml (0–10000)  
Bowel mesenteric carcinomatosis    0.544
 Yes 78 (69.6 %) 160 (66.4 %)  
 No 34 (30.4 %) 81 (33.6 %)  
Residual disease in pelvis    <0.001
 0 cm 92(82.1 %) 129(53.5 %)  
 0.1–0.5 cm 15(13.4 %) 71(29.5 %)  
 0.5–1 cm 3(2.7 %) 41(17.0 %)  
 >1 cm 2(1.8 %) 0(0 %)  
Residual disease in middle abdomen   <0.001
 0 cm 60(53.6 %) 69(28.6 %)  
 0.1–0.5 cm 40(35.7 %) 93(38.6 %)  
 0.5–1 cm 9(8.0 %) 79(32.8 %)  
 >1 cm 3(2.7 %) 0(0 %)  
Total 112 241  
  1. Abbreviations: FIGO International Federation of Gynecology and Obstetrics, ECOG Eastern Cooperative Oncology Group, ASA American Society of Anesthesiologists, NA not available
  2. *Tested by Chi-square or Mann–Whitney U. b Thoracic exploration was performed in 13 patients and 8 patients were upstaged for pleural metastasis