Not stratified analysis | Stratification for gender | ||||||||
---|---|---|---|---|---|---|---|---|---|
Characteristic | OR unadjusted | 95 % CI | OR adjusted b | 95 % CI | ♂OR adjusted c | 95 % CI | ♀OR adjusted c | 95 % CI | |
Age | <65 years a | 3.19* | 1.8–5.7 | 3.40* | 1.8–6.4 | 1.73 | 0.8–3.6 | 7.22* | 2.4–22.1 |
≥65 years | |||||||||
Gender | Male a | 2.41* | 1.4–4.1 | 2.66* | 1.5–4.8 | - | - | - | - |
Female | |||||||||
Comorbidity score (ACE-27) | Low (0–1) a | 1.78* | 1.0–3.0 | 1.49 | 0.8–2.7 | 1.77 | 0.8–3.7 | 1.39 | 0.6–3.3 |
High (2–3) | |||||||||
Tumor stage | Early (I-II) a | 2.22* | 1.2–4.1 | 1.07 | 0.4–2.9 | 2.88* | 1.2–7.1 | 1.92 | 0.8–4.7 |
Advanced (III-IV) | |||||||||
Tumor site | Oral cavity a | - | - | - | - | ||||
Pharynx | 0.78 | 0.4–1.4 | 1.34 | 0.6–3.0 | |||||
Larynx | 0.43* | 0.2–0.9 | 0.82 | 0.3–2.1 | |||||
Prior malignancy | No a | - | - | - | - | ||||
Other prior cancer yet treated | 1.39 | 0.6–3.1 | 1.09 | 0.5–2.6 | |||||
Prior head and neck cancer yet treated | 0.93 | 0.4–2.4 | 0.99 | 0.3–2.9 | |||||
Marital status | Partner a | 2.92* | 1.7–5.0 | 2.25* | 1.2–4.1 | 1.64 | 0.8–3.5 | 3.63* | 1.5–9.0 |
Single | |||||||||
Children | Yes a | - | - | - | - | ||||
No | 2.26* | 1.3–4.1 | 2.08* | 1.0–4.1 | |||||
Unknown | 0.78 | 0.3–1.8 | 1.19 | 0.5 3.0 | |||||
No contact | 1.66 | 0.4–7.5 | 1.19 | 0.2–5.9 | |||||
Standard treatment according to guidelines | Surgery a | - | - | - | - | ||||
Radiotherapy | 0.44 | 0.1–1.6 | 0.29 | 0.07–1.2 | |||||
Chemoradiation | 1.64 | 0.6–4.4 | 1.15 | 0.3–4.6 | |||||
Surgery + radiotherapy | 3.21* | 1.3–8.0 | 2.16 | 0.6–7.6 | |||||
Surgery + chemotherapy | - | - | - | - | |||||
Surgery + PORT on indication | 1.27 | 0.4–3.9 | 1.10 | 0.3–3.8 | |||||
Year of treatment | 2010 a | - | - | - | - | ||||
2011 | 0.89 | 0.5–1.7 | 0.73 | 0.4–1.5 | |||||
2012 | 0.57 | 0.3–1.1 | 0.63 | 0.3–1.3 |