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Table 2 Unadjusted and adjusted OR’s for MDT decision to propose nonstandard treatment

From: Noncompliance to guidelines in head and neck cancer treatment; associated factors for both patient and physician

Characteristic

 

OR unadjusted

95 % CI

OR adjusted b

95 % CI

Age

<65 years a

1.22

0.7–1.9

1.46

0.9–2.4

≥65 years

Gender

Male a

0.72

0.4–1.2

0.72

0.4–1.3

Female

Comorbidity score (ACE-27)

Low (0–1) a

3.06*

1.9–4.8

3.40*

2.0–5.7

High (2–3)

Tumor stage

Early (I-II) a

5.74*

3.0–11.0

3.40*

1.4–8.5

Advanced (III-IV)

Tumor site

Oral cavity a

    

Pharynx

2.75*

1.6–4.9

0.94

0.4–2.2

Larynx

1.69

0.9–3.3

0.85

0.3–2.1

Prior malignancy

No a

    

Other prior cancer yet treated

0.78

0.3–1.6

0.61

0.3–1.5

Prior head and neck cancer yet treated

1.60

0.8–3.1

2.56*

1.1–5.7

Marital status

Partner a

1.83*

1.2–2.9

1.68

1.0–2.9

Single

Children

Yes a

    

No

1.23

0.7–2.1

1.07

0.6–2.0

Unknown

0.79

0.4–1.5

1.31

0.7–2.7

No contact

0.84

0.7–1.1

0.90

0.7–1.1

Standard treatment according to guidelines

Surgery a

    

Radiotherapy

1.37

0.5–4.1

1.31

0.4–4.5

Chemoradiation

8.29*

3.2–21.5

4.79*

1.3–17.1

Surgery + radiotherapy

2.53

0.9–7.0

1.13

0.3–4.0

Surgery + chemotherapy

8.00*

1.6–39.0

4.61

0.7–29.5

Surgery + PORT on indication

0.86

0.2–3.3

0.98

0.2–4.2

Year of treatment

2010 a

    

2011

0.71

0.4–1.3

0.56

0.3–1.1

2012

1.04

0.6–1.7

1.11

0.6 2.0

  1. a = reference value, b = odds ratio calculated using multivariate logistic regression analysis adjusting for age, gender, comorbidity, tumor stage, tumor site, prior malignancy, marital status, having children, standard treatment proposal according to guidelines, year of treatment, * = p value < 0.05