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Table 4 Expression of FOXP1, cyclin D1 and NRP1, as assessed by immunohistochemistry (IPX) for the second validation cohort of 82 BRCA1 and 65 sporadic basal cancers

From: Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers

Predicted target gene Positive IPX in BRCA1, n (%) Positive IPX in sporadic, n (%) p value (chi square) positive or negative on IPX p value (Mann-Whitney) on IPX score out of 7
FOXP1 43 (52 %) 58 (94 %) <0.001 <0.001
Cyclin D1 47 (57 %) 50 (89 %) <0.001 <0.001
NRP1 33 (41 %) 42 (72 %) <0.001 <0.001
CD99 23 (28 %) 26 (47 %) 0.024 0.012