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Table 4 Expression of FOXP1, cyclin D1 and NRP1, as assessed by immunohistochemistry (IPX) for the second validation cohort of 82 BRCA1 and 65 sporadic basal cancers

From: Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers

Predicted target gene

Positive IPX in BRCA1, n (%)

Positive IPX in sporadic, n (%)

p value (chi square) positive or negative on IPX

p value (Mann-Whitney) on IPX score out of 7

FOXP1

43 (52 %)

58 (94 %)

<0.001

<0.001

Cyclin D1

47 (57 %)

50 (89 %)

<0.001

<0.001

NRP1

33 (41 %)

42 (72 %)

<0.001

<0.001

CD99

23 (28 %)

26 (47 %)

0.024

0.012