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Table 2 miRNAs discriminating BRCA1 from sporadic basal cancers (fold change > 2.5, adjusted p < 0.05)

From: Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers

miRNA Adjusted p value Fold change Expression in BRCA1 vs. basal Cytoband Correlation with previous BRCA1 CGH findings
hsa-miR-892a 0.0002 −7.98 Up Xq27.3  
hsa-miR-1247 0.0015 −6.26 Up 14q32.31  
hsa-miR-129-3p 0.0001 −6.03 Up 11p11.2  
hsa-miR-494 0.0014 −5.84 Up 14q31  
hsa-miR-1273 0.0008 −5.43 Up 8q22.2 [53]
hsa-miR-198 0.0004 −5.34 Up 3q13.33 [54]
hsa-miR-30c-1* <0.0001 −4.51 Up 1p34.2  
hsa-miR-1281 0.0001 −3.88 Up 22q13.2  
hsa-miR-220b <0.0001 −3.76 Up 19p13.3  
hsa-miR-566 <0.0001 −3.75 Up 3p21.31  
hsa-miR-603 0.0003 −3.73 Up 10p12.1 [53, 55]
hsa-miR-675 0.0018 −3.53 Up 11p15.5  
hsa-miR-637 0.0012 −3.31 Up 19p13.3  
hsa-miR-576-3p 0.0014 −3.26 Up 4q25  
hsa-miR-638 0.0366 −3.04 Up 19p13.2  
hsa-miR-1826 <0.0001 −3.03 Up 16p11.2 [54]
hsa-miR-1268 0.0218 −2.96 Up 15q11.2 [53]
hsa-miR-1234 0.0076 −2.79 Up 8q24.3 [53, 56]
hsa-miR-1285 0.0428 −2.69 Up 7q21.2  
hsa-miR-509-5p 0.0043 −2.53 Up Xq27.3  
hsa-miR-374b 0.0026 7.00 Down Xq13.2 [53]
hsa-miR-590-3p 0.0101 5.25 Down 7q11.23  
hsa-miR-218 0.0264 4.02 Down 4p15.31 [56]
hsa-miR-335* 0.0428 3.82 Down 7q32.2  
hsa-miR-190b 0.0204 3.81 Down 1q21.3  
hsa-miR-96 0.0405 3.48 Down 7q32.2  
hsa-miR-454* 0.0405 3.21 Down 17q22  
hsa-miR-576-5p 0.0218 3.03 Down 4q25  
hsa-miR-340* 0.0111 3.01 Down 5q35.3 [53]
hsa-miR-29a* 0.0008 3.00 Down 7q32.3  
hsa-miR-148b 0.0014 2.90 Down 17q13.13 [56]
hsa-miR-130b* 0.0076 2.89 Down 22q11.21  
hsa-miR-149 0.0443 2.77 Down 17q37.3  
hsa-miR-10a 0.0076 2.71 Down 17q21.32  
hsa-miR-660 0.0428 2.56 Down Xp11.23