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Table 1 Grade independent basal phenotype miRNA signature in common with other studies [12, 13, 49, 50]

From: Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers

 

miRNA in common with other studies

Unadjusted p value

Adjusted p value

Fold change

Expression in basal vs. luminal

hsa-miR-149

[14, 16]

0.0246

0.2556

−2.21

Down

hsa-miR-29c

[1416, 50, 51]

0.0315

0.2838

−1.22

Down

hsa-miR-29c*

[15, 16, 50]

0.0278

0.2679

−1.61

Down

hsa-miR-109b

[14, 50]

<0.0001

<0.0001*

−11.77

Down

hsa-miR-125a-5p

[14]

0.0203

0.2292

−1.13

Down

hsa-miR-136

[12]

0.0247

0.1120

−1.78

Down

hsa-miR-199a*:9.1

[12]

0.0138

0.0777

−1.47

Down

hsa-miR-342-3p

[1416]

0 < 0.0001

0.0024*

−1.58

Down

hsa-miR-342-5p

[1216, 49]

<0.0001

0.0001*

−1.97

Down

hsa-miR-375

[15, 16, 50]

0.0005

0.0177

−3.56

Down

hsa-let-7c

[12, 15]

0.0020

0.0232*

−1.26

Down

hsa-let-7f

[12]

0.0300

0.1284

−1.11

Down

hsa-let-7a

[12]

0.0467

0.1669

−1.05

Down

hsa-miR-17

[15, 16, 50]

<0.0001

0.0002*

1.74

Up

hsa-miR-17*

[1416, 50]

0.0004

0.0162*

1.30

Up

hsa-miR-18a

[1216, 32, 50, 52]

<0.0001

<0.0001*

5.22

Up

hsa-miR-18b

[1416, 50]

0.0269

0.2676

1.89

Up

hsa-miR-19a

[1416, 50]

0.0006

0.0191*

3.37

Up

hsa-miR-19b

[15, 16]

0.0005

0.0171*

1.90

Up

hsa-miR-93

[12, 13, 16]

0.0001

0.0032*

1.30

Up

hsa-miR-106a

[12, 13, 50]

<0.0001

0.0011*

1.87

Up

hsa-miR-106b

[12, 13, 15, 50]

0.0151

0.0814

1.59

Up

hsa-miR-135b

[1216, 50]

<0.0001

0.0017*

4.44

Up

hsa-miR-142-5p

[12, 13]

0.0019

0.0229*

2.07

Up

hsa-miR-20a

[15, 16]

<0.0001

0.0001*

1.51

Up

hsa-miR-224

[14, 16]

0.0004

0.0162

4.75

Up

hsa-miR-455-5p

[14]

0.0159

0.1986

2.08

Up

hsa-miR-505

[50]

0.0030

0.0741

2.83

Up

hsa-miR-519a

[14]

<0.0001

0.0007*

9.05

Up

hsa-miR-521

[14]

<0.0001

<0.0001*

8.97

Up

hsa-miR-522

[14]

<0.0001

0.0004*

10.79

Up

hsa-miR-9

[14]

0.0069

0.1260

4.60

Up

hsa-miR-9*

[14, 16]

0.0322

0.2838

2.50

Up

hsa-miR-93

[15, 16]

0.0003

0.0142

1.32

Up

  1. *significant p < 0.05 after adjustment for multiple tests