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Table 2 Effect of NCTD on cell cycle distribution of HT-29, HDLECs and Co-culture system (mean ± SD, %)

From: A potential small-molecule synthetic antilymphangiogenic agent norcantharidin inhibits tumor growth and lymphangiogenesis of human colonic adenocarcinomas through blocking VEGF-A,-C,-D/VEGFR-2,-3 “multi-points priming” mechanisms in vitro and in vivo

Groups

HT-29

HDLECs

Co-culture

G2/M

S

G2/M

S

G2/M

S

Control

25.5 ± 3.3

21.7 ± 3.1

16.5 ± 2.3

16.7 ± 2.3

21.5 ± 3.3

18.9 ± 3.0

NCTD (IC50)

28.7 ± 4.8

9.3 ± 1.8*

15.7 ± 2.8*

6.3 ± 1.2*

22.7 ± 2.8*

7.8 ± 1.6*

  1. *P < 0.001, vs. control group