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Table 2 Grade III and IV toxicities according to treatment groups

From: The effectiveness and safety of platinum-based pemetrexed and platinum-based gemcitabine treatment in patients with malignant pleural mesothelioma

Toxicity

Group I

Group II

P*

n (%)

n (%)

Neutropenia

19 (16.3)

3 (10.0)

0.568

Anemia

4 (3.4)

1 (3.3)

1.000

Thrombocytopenia

6 (5.1)

4 (13.3)

0.123

Nause / vomiting

8 (6.9)

5 (16.6)

0.142

Nephrotoxicity

5 (4.3)

-

0.584

Febrile neutropenia

2 (1.7)

2 (6.6)

0.187

  1. Group I: cis/carboplatin + pemetrexed; Group II: cis/carboplatin + gemcitabine; a: Only the worst WHO grade was reported for each patient
  2. *: Fisher’s Exact Test