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Table 2 Grade III and IV toxicities according to treatment groups

From: The effectiveness and safety of platinum-based pemetrexed and platinum-based gemcitabine treatment in patients with malignant pleural mesothelioma

Toxicity Group I Group II P*
n (%) n (%)
Neutropenia 19 (16.3) 3 (10.0) 0.568
Anemia 4 (3.4) 1 (3.3) 1.000
Thrombocytopenia 6 (5.1) 4 (13.3) 0.123
Nause / vomiting 8 (6.9) 5 (16.6) 0.142
Nephrotoxicity 5 (4.3) - 0.584
Febrile neutropenia 2 (1.7) 2 (6.6) 0.187
  1. Group I: cis/carboplatin + pemetrexed; Group II: cis/carboplatin + gemcitabine; a: Only the worst WHO grade was reported for each patient
  2. *: Fisher’s Exact Test