From: Spectrum and frequencies of BRCA1/2 mutations in Bulgarian high risk breast cancer patients
N | Proportion of patients per feature (%) | |
---|---|---|
Age at breast cancer diagnosis | ||
<40 | 76 | 38 |
41–60 | 99 | 49 |
>60 | 25 | 13 |
Bilateral breast cancer | ||
Yes | 30 | 15 |
No | 170 | 85 |
Personal history of ovarian cancer | ||
Yes | 12 | 6 |
No | 188 | 94 |
Family history of breast and ovarian cancer | ||
Cancer in 1st or 2nd relative | ||
Breast cancer dx < 60 | 73 | 36.5 |
Ovarian cancer, any age | 11 | 5.5 |
Male breast cancer, any age | ||
Neither | 104 | 52 |
Unknown | 12 | 6 |
Triple negative (TNBC) | ||
Yes | 28 | 14 |
No | 172 | 86 |
Unknown | ||
Tumor hormone receptor status | ||
Estrogen receptor (ER) | ||
Positive | 89 | 45 |
Negative | 70 | 34 |
Unknown | 41 | 21 |
Pogesteron receptor (PR) | ||
Positive | 80 | 40 |
Negative | 77 | 39 |
Unknown | 43 | 21 |
Her2/neu | ||
Positive | 82 | 41 |
Negative | 60 | 30 |
Unknown | 58 | 29 |
Stage | ||
1 | 48 | 24 |
2 | 103 | 51.5 |
3 | 15 | 7.5 |
4 | 1 | 0.5 |
Unknown | 33 | 16.5 |
Grade | ||
I | 6 | 3 |
II | 70 | 35 |
III | 34 | 17 |
Unknown | 90 | 45 |
All patients | 200 | 100 % |