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Table 3 Distribution of genotype and allele frequencies in with NK/T lymphoma patients and controls

From: LTA + 252A > G polymorphism is associated with risk of nasal NK/T-cell lymphoma in a Chinese population: a case-control study

Genotypes Controls, n (%) Cases, n (%) OR (95 % CI) P value
IL-10 -3575     
  TT 278(93) 117(94) 1  
  TA 22(7) 8(6) 0.86(0.37-1.99) 0.73
  AA 0 0   
  T 578(96) 242(97) 1  
  A 22(4) 8(3) 0.87(0.38-1.98) 0.73
IL-10 -1082     
  AA 237(79) 101(81) 1  
  AG 60(20) 24(19) 0.94(0.55-1.59) 0.81
  GG 3(1) 0(0)   
  A 534(89) 226(90) 1  
  G 66(11) 24(10) 0.86(0.52-1.41) 0.55
IL-10 -819     
  CC 39(13) 9(7) 1  
  CT 125(42) 59(47) 2.00(0.93-4.49) 0.08
  TT 136(45) 57(46) 1.81(0.83-3.99) 0.14
  C 203(34) 76(30)   
  T 397(66) 174(70) 1.17(0.85-1.61) 0.33
IL-10 -592     
  CC 38(13) 9(7) 1  
  AC 124(41) 59(47) 2.00(0.91-4.43) 0.08
  AA 138(46) 57(46) 1.74 (0.79-3.84) 0.17
  C 200(33) 77(31) 1  
  A 400(67) 173(69) 1.12(0.82-1.54) 0.47
TNF-α -857     
  CC 239(79) 96(78) 1  
  CT 56(19) 28(22) 1.25(0.75-2.08) 0.40
  TT 5(1) 1(0) 0.50(0.06-4.32) 0.53
  C 534(89) 220(88) 1  
  T 66(11) 30(12) 1.10(0.69-1.75) 0.68
TNF-α -308     
  GG 260(87) 115(92) 1  
  AG 40(13) 10(8) 0.56 (0.27-1.17) 0.12
  AA 0 0   
  G 560(93) 240(96) 1  
  A 40(7) 10(4) 0.58 (0.29-1.19) 0.14
TNF-α -238     
  GG 267(89) 116(93) 1  
  AG 32(11) 9(7) 0.65(0.30-1.40) 0.27
  AA 1(0) 0(0) -  
  G 566(94) 241(96) 1  
  A 34(6) 9(4) 0.62(0.29-1.32) 0.21
LTA +252     
  GG 56(19) 9(7) 1  
  GA 149(50) 71(57) 2.95(1.34-6.48) 0.01*
  AA 95(31) 45(36) 2.97(1.39-6.33) 0.01*
  GA + AA 244(81) 116(93) 2.96(1.42-6.19) 0.004*
  G 261(44) 89(36) 1  
  A 339(56) 161(64) 1.39(1.03-1.89) 0.03*
CTLA-4 -1661     
  AA 216(72) 84(67) 1  
  AG 78(26) 40(32) 1.32(0.84-2.08) 0.24
  GG 6(2) 1(0) 0.43(0.05-3.61) 0.44
  G 90(15) 42(17) 1  
  A 510(85) 208(83) 0.87(0.59-1.30) 0.51
CTLA-4 -318     
  CC 222(74) 88(70) 1  
  CT 73(24) 36(29) 1.24(0.78-1.99) 0.36
  TT 5(2) 1(0) 0.51(0.05-4.38) 0.54
  C 517(86) 212(85) 1  
  T 83(14) 38(15) 1.11(0.74-1.69) 0.60
CTLA-4 + 49     
  AA 34(11) 8(6) 1  
  GA 118(39) 60(48) 2.16(0.94-4.96) 0.07
  GG 148(49) 57(46) 1.64(0.72-3.75) 0.24
  A 186(31) 76(30) 1  
  G 414(69) 174(70) 0.97(0.71-1.34) 0.86
CTLA-4 CT60     
  AA 10(3) 3(2) 1  
  GA 82(27) 32(26) 1.30(0.34-5.04) 0.70
  GG 208(69) 90(72) 1.44(0.39-5.36) 0.58
  A 102(17) 38(15) 1  
  G 498(83) 212(85) 1.14(0.76-1.71) 0.52
  1. *adjusted for age, sex