Skip to main content

Table 1 Correlation of LVD with clinicopathological parameters and survival

From: The different role of intratumoral and peritumoral lymphangiogenesis in gastric cancer progression and prognosis

Factors (N)

I-LVD

P-LVD

  

mean ± SD

P

mean ± SD

P

Age

<60 (33)

12.60 ± 5.32

N.S.

10.52 ± 3.22

N.S.

 

>60 (33)

11.99 ± 3.15

 

11.53 ± 3.99

 

Sex

Male (47)

12.31 ± 4.79

N.S.

11.06 ± 3.91

N.S.

 

Female (19)

12.24 ± 3.11

 

10.88 ± 2.83

 

Extent of resection

Total gastrectomy (16)

13.78 ± 5.62

N.S.

12.36 ± 5.30

N.S.

 

Subtotal gastrectomy (50)

11.82 ± 3.81

 

10.59 ± 2.87

 

Tumor location

Upper 1/3 (12)

12.01 ± 3.30

N.S.

11.74 ± 5.40

N.S.

 

Middle 1/3 (21)

13.49 ± 5.18

 

11.26 ± 3.63

 
 

Lower 1/3 (32)

12.33 ± 4.37

 

10.63 ± 2.92

 

Tumor size

<5cm (36)

12.20 ± 4.98

N.S.

10.55 ± 3.61

N.S.

 

>5cm (30)

12.40 ± 3.53

 

11.56 ± 3.62

 

Lauren classification

Intestinal type (31)

11.20 ± 3.06

0.048*

10.10 ± 2.74

N.S.

 

Diffuse type (35)

13.26 ± 5.09

 

11.55 ± 4.23

 

Differentiation

Differentiated (31)

11.03 ± 2.80

0.021*

10.49 ± 2.74

N.S.

 

Undifferentiated (35)

13.41 ± 5.15

 

11.47 ± 4.25

 

Tumor stage (AJCC 7th ed.)

T1 (18)

10.22 ± 3.53

0.024*

9.87 ± 3.55

N.S.

 

T2 (11))

12.95 ± 4.09

 

11.70 ± 3.64

 
 

T3 (26)

12.23 ± 3.95

 

11.05 ± 3.74

 
 

T4 (11)

15.16 ± 5.37

 

12.18 ± 3.37

 

LVI

Negative (37)

10.96 ± 3.80

0.004*

10.18 ± 3.71

0.028*

 

Positive (29)

13.99 ± 4.48

 

12.12 ± 3.28

 

Node stage (AJCC 7th ed.)

N0 (36)

11.26 ± 3.84

0.052

10.00 ± 2.77

0.040*

 

N1 (3)

3.34 ± 2.20

 

10.25 ± 0.55

 
 

N2 (7)

13.51 ± 3.79

 

12.38 ± 1.84

 
 

N3 (20)

14.16 ± 5.00

 

12.67 ± 4.38

 

Tumor node metastasis stage (AJCC 7th ed.)

I (20)

10.45 ± 3.93

0.029*

9.81 ± 3.02

0.061

 

II (30)

12.27 ± 3.58

 

10.88 ± 3.18

 
 

III (18)

14.17 ± 5.14

 

12.56 ± 4.48

 

DFS (month)

LVD-Low (38)

57.82 ± 3.07

N.S.

59.31 ± 2.77

0.037*

 

LVD-High (28)

51.45 ± 4.84

 

51.21 ± 4.81

 

OS (month)

LVD-Low (38)

61.70 ± 2.62

0.031*

60.06 ± 2.70

0.088

 

LVD-High (28)

52.60 ± 4.44

 

55.96 ± 4.14

 
  1. LVI, lympho-vascular invasion; DFS, disease free survival; OS, overall survival
  2. *, P <0.05; N.S., not significant; data are expressed as means ± SD