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Fig. 5 | BMC Cancer

Fig. 5

From: The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

Fig. 5

Overexpression of PPARα variants in human and mouse hepatic cell lines. a qRT-PCR analysis of the selected proliferative genes following overexpression of each PPARα isoform and treatment with WY14,643 of mouse AML12 (top) and human hepatoma HuH7 cells (bottom). Error bars represent standard deviations of three independent experiments. b Quantitative qRT-PCR analysis of the selected pro-inflammatory genes following overexpression of each PPARα isoform and treatment with IL-6 of mouse AML12 (top) and human hepatoma HuH7 cells (bottom). Error bars represent standard deviations of three independent experiments. * indicates significance p < 0.05

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