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Table 2 Univariate and adjusted risk differences for colorectal cancer and lung cancer

From: Primary care characteristics and stage of cancer at diagnosis using data from the national cancer registration service, quality outcomes framework and general practice information

  Colorectal cancer Lung cancer
Univariate Adjusted; age & deprivation Univariate Adjusted; age & deprivation
Risk difference (95 % CI) p-value Risk difference (95 % CI) p-value Risk difference (95 % CI) p-value Risk difference (95 % CI) p-value
Patient level Age             
65 + yrs Baseline Baseline Baseline Baseline
45-64 years 6.0 (4.6 to 7.3) <0.001 5.9 (4.6 to 7.3) <0.001 3.1 (1.7 to 4.5) <0.001 3.3 (1.9 to 4.6) <0.001
15-44 years 10.3 (7.1 to 13.4) <0.001 10.1 (6.9 to 13.3) <0.001 4.2 (−1.5 to 9.9) 0.15 4.5 (−1.2 to 10.2) 0.12
Sex             
Male Baseline Baseline Baseline Baseline
Female 0.1 (−1.1 to 1.4) 0.82 0.0 (−1.2 to 1.2) 1.00 −3.1 (−4.1 to −2.1) <0.001 −3.3 (−4.3 to −2.3) <0.001
Ethnicity             
White Baseline   Baseline  
Non-white 6.7 (2.7 to 10.7) 0.001     −0.7 (−4.6 to 3.1) 0.71    
Deprivation             
Q1 (least deprived) Baseline Baseline Baseline Baseline
Q2 −0.4 (−2.2 to 1.4)   −0.3 (−2.1 to 1.5)   −0.5 (−2.2 to 1.3)   −0.4 (−2.2 to 1.4)  
Q3 −0.3 (−2.2 to 1.5)   −0.3 (−2.1 to 1.6)   0.3 (−1.4 to 2.1)   0.4 (−1.3 to 2.1)  
Q4 1.0 (−0.9 to 2.9)   0.9 (−1.0 to 2.8)   −0.3 (−2.0 to 1.4)   −0.4 (−2.1 to 1.3)  
Q5 (most deprived) 1.5 (−0.6 to 3.5) 0.07 1.1 (−0.9 to 3.1) 0.14 −1.0 (−2.7 to 0.7) 0.29 −1.3 (−3.0 to 0.4) 0.13
GP demographics Number of patients per GP             
Q1 (lowest) Baseline Baseline Baseline Baseline
Q2 1.0 (−0.9 to 2.9)   1.1 (−0.8 to 3.0)   0.5 (−1.1 to 2.2)   0.6 (−1.0 to 2.2)  
Q3 1.1 (−0.9 to 3.1)   1.1 (−0.9 to 3.1)   0.6 (−1.0 to 2.3)   0.7 (−0.9 to 2.3)  
Q4 1.6 (−0.3 to 3.6)   1.5 (−0.4 to 3.4)   1.7 (0.1 to 3.3)   1.7 (0.2 to 3.3)  
Q5 (highest) 0.4 (−1.6 to 2.4) 0.54 0.2 (−1.8 to 2.1) 0.74 2.0 (0.4 to 3.5) 0.01 1.8 (0.2 to 3.4) 0.01
Training practice             
No Baseline Baseline Baseline Baseline
Yes 0.2 (−1.0 to 1.5) 0.71 0.0 (−1.2 to 1.3) 0.95 0.6 (−0.5 to 1.6) 0.27 0.6 (−0.5 to 1.6) 0.28
GPs aged 50 and over             
Some Baseline Baseline Baseline Baseline
None −1.2 (−3.5 to 1.1) 0.30 −1.4 (−3.6 to 0.9) 0.24 −2.6 (−4.3 to −0.8) 0.01 −2.5 (−4.3 to −0.7) 0.01
All 0.9 (−1.7 to 3.4) 0.52 0.5 (−2.1 to 3.1) 0.69 2.0 (−0.1 to 4.1) 0.07 2.0 (−0.1 to 4.1) 0.06
GPs female             
Some Baseline Baseline Baseline Baseline
None −0.4 (−2.7 to 1.9) 0.73 −0.8 (−3.1 to 1.6) 0.53 1.3 (−0.5 to 3.1) 0.17 1.3 (−0.5 to 3.1) 0.14
All −3.0 (−8.2 to 2.2) 0.27 −3.5 (−8.7 to 1.7) 0.19 −4.5 (−8.4 to −0.6) 0.03 −4.6 (−8.4 to −0.7) 0.02
GPs qualified in UK             
Some Baseline Baseline Baseline Baseline
None −0.1 (−2.7 to 2.6) 0.95 −0.5 (−3.2 to 2.2) 0.71 −0.6 (−2.6 to 1.5) 0.59 −0.5 (−2.6 to 1.5) 0.61
All −0.6 (−2.0 to 0.7) 0.35 −0.4 (−1.8 to 0.9) 0.51 −0.2 (−1.3 to 0.9) 0.68 −0.3 (−1.4 to 0.8) 0.61
GP level deprivation             
Q1 (least deprived) Baseline Baseline Baseline Baseline
Q2 −1.2 (−3.1 to 0.7)   −1.4 (−3.3 to 0.6)   −1.8 (−3.5 to −0.1)   −1.8 (−3.5 to −0.1)  
Q3 −1.0 (−2.9 to 0.8)   −1.3 (−3.3 to 0.7)   −0.3 (−2.0 to 1.4)   −0.6 (−2.3 to 1.2)  
Q4 0.5 (−1.4 to 2.5)   −0.2 (−2.4 to 1.9)   −0.9 (−2.5 to 0.8)   −1.2 (−3.0 to 0.7)  
Q5 (most deprived) 0.9 (−1.2 to 3.0) 0.17 −0.4 (−2.9 to 2.1) 1.00 −2.6 (−4.3 to −0.9) 0.03 −2.8 (−4.8 to −0.8) 0.04
GP rurality             
Urban > 10 K Baseline Baseline Baseline Baseline
Town and fringe −0.7 (−2.5 to 1.0) 0.40 −0.1 (−1.9 to 1.6) 0.87 0.0 (−1.5 to 1.5) 0.96 −0.2 (−1.7 to 1.4) 0.83
Village, hamlet & isolated dwellings −0.3 (−3.5 to 2.8) 0.84 0.2 (−2.9 to 3.3) 0.90 0.7 (−2.5 to 3.9) 0.67 0.4 (−2.9 to 3.6) 0.82
GP general performance Able to book appointment             
90 % and over Baseline Baseline Baseline Baseline
80-90 % 0.1 (−1.2 to 1.4)   −0.1 (−1.4 to 1.2)   −0.7 (−1.7 to 0.4)   −0.5 (−1.6 to 0.6)  
<80 % 1.1 (−1.3 to 3.5) 0.46 0.3 (−2.1 to 2.7) 0.95 −0.5 (−2.4 to 1.4) 0.32 −0.3 (−2.2 to 1.7) 0.52
Able to see preferred GP             
80 % and over Baseline Baseline Baseline Baseline
60-80 % −0.6 (−2.0 to 0.9)   −0.6 (−2.1 to 0.8)   −1.4 (−2.6 to −0.2)   −1.3 (−2.5 to 0.0)  
<60 % 0.5 (−1.3 to 2.3) 0.65 0.1 (−1.7 to 1.9) 0.96 −1.4 (−2.8 to 0.0) 0.05 −1.2 (−2.6 to 0.2) 0.09
Total QOF points             
990 to 1000 (max) points Baseline Baseline Baseline Baseline
980 to 989 points 0.1 (−1.4 to 1.7)   0.0 (−1.6 to 1.5)   −0.8 (−2.1 to 0.5)   −0.7 (−2.0 to 0.6)  
960 to 979 points 0.6 (−1.2 to 2.4)   0.4 (−1.4 to 2.2)   −0.4 (−1.8 to 1.0)   −0.5 (−1.9 to 0.9)  
<960 points −0.5 (−2.5 to 1.4) 0.93 −0.9 (−2.8 to 1.1) 0.53 −0.8 (−2.4 to 0.8) 0.29 −0.7 (−2.3 to 0.9) 0.65
GP specific cancer activities Two week wait referral rate             
Q1 (lowest) Baseline Baseline Baseline Baseline
Q2 0.3 (−1.6 to 2.3)   0.6 (−1.3 to 2.5)   −1.6 (−3.2 to −0.1)   −1.6 (−3.2 to −0.1)  
Q3 −0.6 (−2.5 to 1.3)   −0.3 (−2.2 to 1.7)   −2.3 (−3.8 to −0.7)   −2.3 (−3.9 to −0.8)  
Q4 −0.7 (−2.6 to 1.3)   −0.2 (−2.1 to 1.8)   −2.1 (−3.7 to −0.5)   −2.0 (−3.6 to −0.5)  
Q5 (highest) −1.2 (−3.1 to 0.8) 0.13 −0.6 (−2.6 to 1.4) 0.39 −3.4 (−5.0 to −1.8) <0.001 −3.3 (−4.9 to −1.7) <0.001
Two week wait conversion             
Q1 (lowest) Baseline Baseline Baseline Baseline
Q2 0.8 (−1.2 to 2.7)   1.0 (−1.0 to 3.0)   1.3 (−0.3 to 3.0)   1.5 (−0.1 to 3.1)  
Q3 −2.5 (−4.5 to −0.5)   −2.0 (−4.0 to −0.1)   1.2 (−0.4 to 2.9)   1.3 (−0.4 to 2.9)  
Q4 −1.8 (−3.7 to 0.2)   −1.3 (−3.2 to 0.7)   3.6 (2.0 to 5.2)   3.6 (2.0 to 5.2)  
Q5 (highest) 0.6 (−1.3 to 2.6) 0.56 1.2 (−0.7 to 3.1) 0.96 4.1 (2.5 to 5.7) <0.001 4.0 (2.4 to 5.6) <0.001
Two week wait detection             
Q1 (lowest) Baseline Baseline Baseline Baseline
Q2 1.5 (−0.5 to 3.4)   1.7 (−0.2 to 3.7)   −1.1 (−2.7 to 0.5)   −1.1 (−2.6 to 0.5)  
Q3 0.7 (−1.2 to 2.6)   0.9 (−0.9 to 2.8)   −1.0 (−2.5 to 0.6)   −0.8 (−2.4 to 0.7)  
Q4 −1.2 (−3.3 to 0.9)   −0.8 (−2.9 to 1.2)   −0.7 (−2.3 to 0.9)   −0.6 (−2.2 to 1.1)  
Q5 (highest) 1.3 (−0.6 to 3.3) 0.92 1.6 (−0.4 to 3.5) 0.72 −1.3 (−2.9 to 0.3) 0.22 −1.3 (−2.9 to 0.3) 0.23
GP other activities Average colonoscopy, sigmoidoscopy and upper GI endoscopy             
T1 (lowest) Baseline Baseline Baseline Baseline
T2 −0.3 (−1.8 to 1.2)   0.0 (−1.5 to 1.5)   −1.1 (−2.4 to 0.1)   −1.1 (−2.3 to 0.2)  
T3 (highest) −2.4 (−3.9 to −0.9) 0.002 −2.0 (−3.5 to −0.5) 0.01 −0.7 (−2.0 to 0.5) 0.27 −0.5 (−1.7 to 0.8) 0.48
Emergency admissions             
Q1 (lowest) Baseline Baseline Baseline Baseline
Q2 −0.2 (−2.1 to 1.8)   0.2 (−1.8 to 2.1)   0.4 (−1.3 to 2.0)   0.4 (−1.2 to 2.1)  
Q3 −0.7 (−2.6 to 1.3)   −0.3 (−2.2 to 1.7)   1.0 (−0.6 to 2.7)   1.0 (−0.6 to 2.7)  
Q4 −0.7 (−2.7 to 1.3)   −0.2 (−2.2 to 1.7)   0.8 (−0.8 to 2.3)   0.9 (−0.7 to 2.5)  
Q5 (highest) −0.9 (−2.8 to 1.1) 0.32 −0.3 (−2.2 to 1.7) 0.66 1.3 (−0.3 to 2.9) 0.10 1.6 (0.0 to 3.2) 0.04