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Table 2 The dose-effect of agents on ETS-1′s transcriptional activity

From: Estrogen receptor α enhances the transcriptional activity of ETS-1 and promotes the proliferation, migration and invasion of neuroblastoma cell in a ligand dependent manner

Agents

IC 50 /EC 50 (nM)

IC max /EC max (μM)

R2 Value

P Value

E2

18.75 ± 1.22

0.10

0.94

0.0024

HGF

6.22 ± 0.75 (ng/ml)

0.03

0.95

0.0098

ICI-182780

26.53 ± 4.15

0.10

0.92

0.015

ARQ-197

17.75 ± 3.66

0.30

0.91

0.0044

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BMC Cancer

ISSN: 1471-2407

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