Fig. 2From: Estrogen receptor α enhances the transcriptional activity of ETS-1 and promotes the proliferation, migration and invasion of neuroblastoma cell in a ligand dependent mannerThe effect of estrogen and HGF on the expression of ETS-1 targeted genes. SH-SY5Y cells were treated with indicated concentration of E2, ICI-182780, HGF or ARQ-197. a Identification of ETS-1 responsive genes’ mRNA level by Real-time RT-PCR assays. Cells were treated with indicated concentration of agents, and then be examined by RT-PCR assays. b The protein level of ETS-1, MMP1/9 and ERα was identified by Western blot. The values are the mean ± SD from three independent experiments. * P < 0.05Back to article page