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Fig. 1 | BMC Cancer

Fig. 1

From: Estrogen receptor α enhances the transcriptional activity of ETS-1 and promotes the proliferation, migration and invasion of neuroblastoma cell in a ligand dependent manner

Fig. 1

The effect of estrogen on ETS-1 transcriptional activity. SH-SY5Y cells were co-transfected with EBS (a-e), mmp1 (f), mmp9 (g), c-Met (h) and uPA (i) reporters; then treated with indicated concentration of E2 (17-β-estradiol, the agonist of ERα), ICI-182780 (the antagonist of ERα), HGF (hepatocyte growth factor, the agonist of c-Met) or ARQ-197 (the antagonist of c-Met). Cells were harvested and determined by the Luciferase assays. The values are the mean ± SD from three independent experiments. * P < 0.05

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BMC Cancer

ISSN: 1471-2407

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