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Fig. 3 | BMC Cancer

Fig. 3

From: Prospective cohort study using the breast cancer spheroid model as a predictor for response to neoadjuvant therapy – the SpheroNEO study

Fig. 3

Receiver operator curves (ROC) displaying the sensitivity and specificity of (a) the breast cancer spheroid, (b) a multifactor model with baseline predictive factors (ER, PR, HER2, and age) impacting pCR, (c) model combining the breast cancer spheroid model, HER2-Status and type of therapy, and (d) breast cancer spheroid model combined with the factor of treatment adherence defined as treatment discontinuation, dose-reduction or change of treatment. The resulting area under the curve (AUC) is displayed at the top of each curve

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