|
Factors
|
CT + surgery and/or RT n. pts 21 (49 %)
|
CT only n. pts 22 (51 %)
|
p value
|
|---|
|
Gender
|
|
Female
|
10 (49)
|
11 (50)
|
0.9
|
|
Male
|
11 (51)
|
11 (50)
|
|
Median age
|
50 years (range 27–75 years)
|
53 years (range 38–80 year)
|
0.4
|
|
MGMT promoter status
|
|
Methylated
|
9
|
9
|
0.9
|
|
Unmethylated
|
4
|
4
|
|
Unknown
|
8
|
9
|
|
IDH mutation
|
|
Present
|
5
|
1
|
0.17
|
|
Absent
|
8
|
12
|
|
Unknown
|
8
|
9
|
|
KPS
|
|
100
|
11
|
0
|
<0.01
|
|
90
|
5
|
14
|
|
80
|
2
|
0
|
|
70
|
3
|
8
|
|
Time to Relapse from initial diagnosis
|
|
≤ 12 months
|
6
|
15
|
<0.01
|
|
> 12–24 months
|
7
|
6
|
|
> 24 months
|
8
|
1
|
|
Median volume of recurrent disease (cm3)
|
|
< 35 cm3
|
10
|
10
|
0.7
|
|
≥ 35 cm3
|
11
|
12
|
- MGMT methylguanine-DNA methyltransferase, IDH Isocitrate dehydrogenase
