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Table 1 Patients characteristics and treatments at diagnosis

From: Multimodality therapy approaches, local and systemic treatment, compared with chemotherapy alone in recurrent glioblastoma

 

No. (%)

Sex

 Female

21 (49)

 Male

22 (51)

Median age years (range)

51 (27–80)

MGMT promoter methylation status

 Methylated

18 (42)

 Unmethylated

8 (19)

 Unknown

17 (39)

IDH mutation

 Present

6 (14)

 Absent

20 (47)

 Unknown

17 (39)

KPS

 100

11 (26)

 90

19 (44)

 80

2 (4)

 70

11 (26)

Time to Relapse from initial diagnosis

  ≤ 12 months

21 (49)

  > 12–24 months

13 (30)

  > 24 months

9 (21)

Treatment at Initial Diagnosis

 Surgery

43 (100)

 Complete Resection (CR)

24 (56)

 Subtotal Resection (SR)

5 (12)

 Partial Resection (PR)

12 (28)

 Biopsy

2 (4)

 Radiotherapy

43 (100)

 CT Concomitant and adjuvant (TMZ)

43 (100)

  1. MGMT methylguanine-DNA methyltransferase, IDH isocitrate dehydrogenase, KPS karnofsky performance status, TMZ Temozolomide