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Table 1 Infectivity of Ad5 and AdF35 to esophageal carcinoma cells and CAR expression levels

From: Cytotoxic effects of replication-competent adenoviruses on human esophageal carcinoma are enhanced by forced p53 expression

Cells p53 status Mutated codon CAR expression GFP-positive cells (%)
Ad5 AdF35
TE-1 mutated Codon 272 6.57 8.06 ± 1.17 53.47 ± 0.10
TE-2 wild-type   19.22 0.79 ± 0.14 10.15 ± 0.44
TE-10 mutated Codon 242 14.73 16.15 ± 0.52 35.33 ± 0.67
TE-11 wild-type   22.25 22.86 ± 0.53 42.82 ± 0.74
YES-2 mutated Codon 236 0.19 5.09 ± 1.29 51.54 ± 0.36
YES-4 wild-type   26.87 27.18 ± 0.16 61.23 ± 0.07
YES-5 mutated Codon 280 15.40 22.18 ± 0.32 69.97 ± 0.89
YES-6 wild-type   30.23 16.59 ± 0.25 27.63 ± 0.17
T.Tn mutated Codon 214 and 258 8.12 0.49 ± 1.00 21.60 ± 0.15
HEK293    56.97 87.20 ± 0.52 78.05 ± 0.70
  1. Cells were infected with Ad5/GFP or AdF35/GFP at a 30 MOI and were analyzed for the fluorescence with flow cytometry. Averages and the SEs are shown (n = 3). CAR expression levels were determined with flow cytometry and are expressed with an arbitrary unit