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Table 1 The Combination Index (C.I.) values after combined treatment with MK1775 and AZD7762

From: Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma

Cell line

Average C.I. value*

Standard deviation

WM239

0.3

±0.1

WM45.1

0.9

±0.3

WM983B

0.7

±0.4

WM1366

0.6

±0.4

FEMX-1

0.4

±0.1

“Patient 3”

1.0

±0.2

  1. *C.I. values are estimated from the dose response effects presented in Additional file 1: Figure S1A and 1B