Table 4 Clinical and pathological characteristics according to intratumor cholesteryl esters content tertile
Variables | Control N = 20 | CE-rich N = 10 | p-value |
|---|---|---|---|
Age (years) | 65.5 (49.8-78.3) | 53 (45.5-73.0) | 0.267 |
Clinicopathological parameters | |||
Breast carcinoma type | 0.015* | ||
Luminal-A (%) | 10 (50) | 0 (0) | |
Her-2 (%) | 6 (30) | 4 (40) | |
TN (%) | 4 (20) | 6 (60) | |
Nottingham combined histologic grade | 0.024* | ||
Grade I (%) | 6 (30) | 0 (0) | |
Grade II (%) | 4 (20) | 0 (0) | |
Grade III (%) | 10 (50) | 10 (100) | |
TNM Stage | 0.636 | ||
Stage I-II (%) | 17 (85) | 8 (80) | |
Stage III-IV (%) | 3 (15) | 1 (10) | |
Unknown (%) | 0 (10) | 1 (10) | |
Tumor size (units) | 2.40 (1.85-3.87) | 3.25 (2.57-4.00) | 0.231 |
Lymph node affected (%) | 7 (35) | 3 (30) | 0.560 |
Vascular invasion (%) | 2 (10) | 2 (20) | 0.407 |
Tumor necrosis (%) | 4 (20) | 8 (80) | 0.003* |
Ki-67 (%) | 8.50 (5.00-28.75) | 65.00 (37.50-82.50) | <0.001* |
Ki-67 over 20 (%) | 6 (30) | 9 (90) | 0.003* |
Other conditions | |||
Dyslipidemia (%) | 7 (35) | 4 (40) | 0.466 |
Menopause(%) | 11 (55) | 4 (40) | 0.603 |
Intratumor lipid parameters | |||
CE (μg/mg protein) | 2.59 (1.29-3.30) | 7.30 (5.94-8.67) | <0.001* |
TG (μg/mg protein) | 4.31 (2.07-18.70) | 7.36-14.38) | 0.502 |
Free Chl (μg/mg protein) | 4.89 (4.24-5.25) | 5.18 (4.71-6.29) | 0.155 |