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Table 3 Clinical and pathological characteristics according to breast carcinoma type

From: Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study

Variables

Luminal-A

Her-2

TN

 
 

N = 10

N = 10

N = 10

p-value

Age (years)

66.5 (46.8-85.3)

54.0 (49.8-63.0)

68.5 (50.8-76.0)

0.477

Clinicopathological parameters

    

Nottingham combined histologic grade

   

<0.001*

 Grade I (%)

5 (50)

0 (0)

1 (10)

 

 Grade II (%)

4 (40)

0 (0)

0 (0)

 

 Grade III (%)

1 (10)

10 (100)

9 (90)

 

TNM Stage

   

0.779

 Stage I-II (%)

9 (90)

8 (80)

8 (80)

 

 Stage III-IV (%)

1 (10)

1 (10)

2 (20)

 

 Unknown (%)

0 (10)

1 (10)

0 (10)

 

Tumor size (cm)

2.25 (1.88-3.62)

2.75 (1.73-4.12)

3.25 (2.57-4.25)

0.349

Lymph node affected (%)

4 (40)

3 (30)

3 (30)

0.861

Vascular invasion (%)

1 (10)

2 (20)

1 (10)

0.749

Tumor necrosis (%)

1 (10)

6 (60)

5 (50)

0.054

Ki-67 (%)

5.00 (4.50-7.75)

30.00 (12.50-42.50)a

65.00 (21.25-82.50) b

0.001*

Ki-67 over 20 (%)

0 (0)

7 (70)

8 (80)

0.001*

Other conditions

    

Dyslipidemia (%)

2 (20)

1 (10)

8 (80)

0.003*

Menopause (%)

5 (50)

6 (60)

4 (40)

0.537

  1. Data are presented as medians (interquartile ranges) for continuous variables and as frequencies (percentages) for categorical variables
  2. p-values by Krusall-Wallis test, Pearson´s Chi square test or Fisher’s exact test when corresponding
  3. *Statistically significant
  4. For continuous variables U Mann–Whitney test was performed when Krusall-Wallis test was significant: aLuminal-Avs.Her-2; bLuminal-Avs. TN; c Her-2vs. TN
  5. CE: Cholesteryl Esters; Free Chl: Free Cholesterol; Her-2: Human Epidermal Growth Factor Receptor 2; TG: Triglycerides; TN: Triple Negative