Table 2 Mediators of tumor lipid homeostasis and invasion
Marker | Abbreviation | Probe ID |
|---|---|---|
Tumor Lipid Homeostasis | ||
Lipid internalization | ||
Low density lipoprotein receptor-related protein 1 | LRP1 | Hs00233899_m1 |
Cluster of Differentiation 36 | CD36 | |
Very low-density lipoprotein receptor | VLDLR | Hs01045922_m1 |
Low-density lipoprotein receptor | LDLR | Hs00181192_m1 |
Scavenger receptor class B member 1 | Gene:SCARB1 | |
Protein: SR-BI | ||
Lipid efflux | ||
ATP-binding cassette transporter | ABCA1 | Hs01059118_m1 |
Cholesterol synthesis | ||
3-hydroxy-3-methyl-glutaryl-CoA reductase | HMG-CoAR | Hs00168352_m1 |
Fatty acid synthesis | ||
Fatty acid synthase | FASN | Hs01005622_m1 |
Cholesterol esterification | ||
Acetyl-Coenzyme A acetyltransferase 1 | ACAT1 | Hs00608002_m1 |
Cholesterol management | ||
Caveolin-1 | CAV1 | Hs00971716_m1 |
Liver X receptor α | LXR-α | Hs00172885_m1 |
Sterol regulatory element-binding transcription factor 1 | SREBP1 | Hs00231674_m1 |
Sterol regulatory element-binding transcription factor 2 | SREBP2 | Hs00190237_m1 |
Tumor Invasion | ||
Matrix metalloproteinase-2 | MMP-2 | Hs00234422_m1 |
Matrix metalloproteinase-9 | MMP-9 | Hs00234579_m1 |
Tissue inhibitor of metalloproteinase 1 | TIMP1 | Hs01092511_m1 |
Cathepsin S | CTSS | Hs00175407_m1 |